Our Mission
The Genomics Technology Laboratory is an integrated, high-throughput molecular biology laboratory focusing on the development of genetics and genomics technologies, data analysis, and information management tools, in support of CCR Investigators. The laboratory develops integrated strategies using multiple technology platforms that maximize the value of research or clinical samples and lead to the identification of pathways, genes, or gene products involved in the development of disease, as well as the assembly of genetic or expression profiles for the identification of prognostic and diagnostic indicators. The laboratory also specializes in the development of custom genomics assays for quantitation and identification of specific molecules in complex clinical samples. GTL is operated by Leidos Biomedial Research Inc. on behalf of NCI as part of the Frederick National Laboratory.
Technology Platforms
Next Generation Sequencing
- Illumina NextSeq, MiSeq
- Whole exome capture
- ImmunoSEQ T-cell receptor sequencing
- Retroviral integration site analysis
DNA Assay/Mutation Detection
- Global DNA methylation
- CpG methylation quantification
- SNP or mutation detection
- DNA extraction and QC
RNA Assay/Gene Expression
- NanoString nCounter platform for gene expression
- HTG EdgeSeq platform for gene expression
- PanCancer Immune panels
- Digital Droplet PCR (ddPCR)
- Low-cost global gene expression
User Guidelines
GTL is operated by Leidos Biomedial Research Inc. on behalf of NCI as part of the Frederick National Laboratory. The laboratory is an open core laboratory serving all CCR investigators. Excess capacity can be made available to other NIH Investigators on a case-by-case basis.
Contact Details
Xiaolin Wu, PhD
Phone: 301.846.7677
Email: forestwu@mail.nih.gov
Group Email: CCRGenomicsTechnologyLab@mail.nih.gov
Address:
Advanced Technology Research Facility, FNLCR
8560 Progress Drive, Frederick, MD 21702