Spatial Proteomics:
PCL is developing methods for global proteomics profiling of samples generated from distinct region(s) within a specimen such as tissue, tumors or other biological samples that would benefit from analysis of spatially confined region. Processing methods will be developed for both fresh and fixed tissue samples. Sample will be collected by Lacer Capture Microdissection (LCM) and/or other precision dissection methods, followed by samples processing and mass spectrometry analysis optimized for maximizing the identification of protein in sample with very low starting material.
