Supported by CCR Office of Science and Technology Resources (OSTR)

OSTR
Cancer Research Technology Program

The CCR Office of the Director has established CCR-dedicated core laboratories that are associated with the Cancer Research Technology Program (CRTP)

The Cancer Research Technology Program (CRTP) leads scientific initiatives and provides technical solutions to carry out biomedical research at the National Cancer Institute (NCI). The Center for Cancer Research (CCR) has established dedicated core facilities associated with the (CRTP), whose services are accessed via the NCI at Frederick Accessioning System (NAS).

CCR/CRTP Core Facilities

For an outline of technical capabilities, available services, and contact information, click on the images below.

Single Cell

The rapid advancement of single-cell technology has provided new powerful tools to answer many biological questions, such as identifying new or rare cell populations and characterizing the complexities of tumor heterogeneity.

Sequencing Facility

The mission of the (SF) is to utilize high-throughput sequencing technologies to enrich cancer research and ensure that the NCI community can leverage the leading-edge of Next-Generation Sequencing technology.

Genomics Technology

The Genomics Technology Laboratory is an integrated, high-throughput molecular biology laboratory focusing on the development of genetics and genomics technologies, together with associated laboratory automation systems, data analysis, and information management tools.

Protein Expression

The Protein Expression Laboratory develops, improves, and delivers protein-centric services. Our goal is to help client investigators achieve their research goals with the lowest possible cost in the shortest time. All PEL services are available individually as well as part of larger projects.

Protein Characterization

PCL offers various technologies to characterize proteins and metabolites. The laboratory develops and applies state-of-the-art analytical technologies, primarily mass spectrometry, liquid chromatography, and Surface Plasmon Resonance (SPR), to advance the understanding of cellular function at the protein, proteomics, metabolite and metabolomic levels.

Electron Microscopy

The EML provides Transmission Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM) services as well as expertise in the following specialized areas: Immunoelectron microscopy, cryo-electron microscopy, negative stain analysis, ultrastructure analysis, and virus particle characterization.

CCR volume-EM (CvEM)

The (CvEM) facility has been developing and applying (CvEM) techniques to image cells and tissues; these include focused ion beam scanning electron microscopy (FIB-SEM) and more recently array tomography (AT), as well as other complementary methods.

Optical Microscopy

OMAL provides the Center for Cancer Research (CCR) with cutting-edge fluorescence microscopy (confocal and super-resolution) for answering cancer and HIV biology research questions.