Core Capabilities
The Mass Cytometry Core (MCC) at the Frederick National Laboratory for Cancer Research, now available to all CCR researchers, provides access to cutting-edge platforms and expert technical support for high-dimensional single-cell analysis and spatial proteomic profiling.
A central expertise of the core is Imaging Mass Cytometry (IMC), which allows simultaneous quantification of dozens of protein markers in intact tissue sections at single-cell resolution while preserving spatial context. This approach enables in-depth analysis of tissue architecture, micro-environments, and cellular interactions. In addition, the MCC provides suspension mass cytometry (CyTOF) for high-parameter profiling of dissociated cells, supporting comprehensive phenotypic and functional analysis of complex cellular populations. Together, these complementary technologies facilitate detailed investigation of cellular heterogeneity and spatial organization, providing powerful insights into complex biological systems and disease processes.
Support for non-NCI investigators is dependent on the capacity of the Core.
For Service Requests
To request services from this CCR dedicated core facility, you must submit your requisition through NAS.