Assay-Development Services

Our group develops and optimizes specialized genomics assays used in cancer research and diagnosis. Here are the lists of specialized assays we offer as services to CCR investigators:

Liquid Biopsy Assays

In the rapidly evolving field of oncology, liquid biopsy assays play a crucial role in the detection and characterization of tumors.

  • cfDNA/ctDNA extraction and QC from plasma and other biofluid
  • cfDNA/ctDNA based rare tumor mutation detection assay
  • cfDNA/ctDNA based methylation assay for tumor signature detection
  • cfDNA fragmentomics analysis
  • cfDNA/ctDNA custom designed assays

Immunotherapy Related Assays

Explore advanced immunotherapy-related assays that enhance our understanding of receptor dynamics and behavior.

  • TCR sequencing based on DNA
  • TCR sequencing based on RNA
  • Vector integration site analysis for CART and TCRT clonality analysis or clonal expansion analysis

CRISPR Cas9 sgRNA Library Screening

These innovative sequencing assays play a crucial role in advancing our understanding of cancer biology

  • Wide collection of multiplex primers for most sgRNA libraries
  • Special primers to deal with low diversity sequencing issues

Cancer Detection Assays

Discover key assays that are essential for advancing immunotherapy research.

  • WES for FFPE or cancer samples with limited input
  • Targeted and high sensitivity assay for specific genes

DNA Assays

Our cutting-edge DNA analysis combines industry-leading platforms to deliver comprehensive extraction and interpretation.

  • Bisulfite sequencing
  • EMseq on gDNA or cfDNA
  • Biomodal 5mC and 5hmC on gDNA or cfDNA
  • Targeted DNA methylation for specific CpGs or Genes
  • DNA mutation and methylation Duo assay

RNA Assay & Gene Expression

Our RNA assay and gene expression services leverage the power of leading technologies to deliver precise, scalable, and actionable transcriptomic insights .

  • Takara RNA based TCRseq
  • Low-cost global gene expression